Tetrahedron Letters

An efficient approach to 2, 5-anhydro-glucitol-based 1′-homo-N-nucleoside mimetics

B Bhatt, RJ Thomson, M von Itzstein

文献索引：Bhatt, Beenu; Thomson, Robin J.; Von Itzstein, Mark Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2741 - 2743

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被引用次数: 5

摘要

Abstract This Letter describes an efficient synthesis of a range of 1′-homo-N-nucleoside mimetics with a series of 4-substituted 1, 2, 3-triazoles replacing the natural nucleobase. The synthesis of 6-O-monosulfated 1′-homo-N-nucleoside mimetic derivatives is also discussed.