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Heterocycles

Regioselective bromination of methoxy derivatives of ethyl indole-2-carboxylate [synthetic studies of indoles and related compounds. XXX]

M Tani, H Ikegami, M Tashiro, T Hiura, H Tsukioka…

文献索引:Tani, Masanobu; Ikegami, Hiroyo; Tashiro, Mayumi; Hiura, Tetsuji; Tsukioka, Hiroko; et al. Heterocycles, 1992 , vol. 34, # 12 p. 2349 - 2362

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被引用次数: 26

摘要

Résumé/Abstract Bromination of ethyl methoxyindole-2-carboxylates (1) with bromine in acetic acid proceeded on the benzene moiety of 1, whereas the reaction of 1 with pyridinium bromide perbromide in pyridine or N-bromosuccinimide in dimethylformamide gave ethyl 3- bromo-methoxyindole-2-carboxylates (2)