Helvetica chimica acta

Distamycin??NA: A DNA Analog with an Aromatic Heterocyclic Polyamide Backbone. Part 1. Synthesis and structural analysis of monomers and dimers containing the …

G Sauter, E Stulz, C Leumann

文献索引：Sauter, Guido; Stulz, Eugen; Leumann, Christian Helvetica Chimica Acta, 1998 , vol. 81, # 1 p. 14 - 34

被引用次数: 7

摘要

Abstract The synthesis of the monomeric building block 13 and its constitutional isomer 12 of a new type of DNA analog, distamycin-NA, is presented (Schemes 1 and 2). This building block consists of a uracil base attached to a thiophene core unit via a biaryl-like axis. Next to the biaryl-like axis on the thiophene chromophore, a carboxy and an amino substituent are located allowing for oligomerization via peptide coupling. The proof of constitution and the ...

22288-79-5

3-乙酰氨基噻吩-2-甲酸甲酯

~51%

~80%

~35%

Potent selective thienoxazinone inhibitors of herpes proteas...

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