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Tetrahedron Letters

Iodine-catalyzed one-pot synthesis of amides from nitriles via Ritter reaction

P Theerthagiri, A Lalitha, PN Arunachalam

文献索引:Theerthagiri, Palani; Lalitha, Appaswami; Arunachalam, Pirama Nayagam Tetrahedron Letters, 2010 , vol. 51, # 21 p. 2813 - 2819

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被引用次数: 47

摘要

Modification of already existing synthetic methodologies has received greater attention in recent years from both industrial and academic research communities. The construction of carbon–nitrogen bond is one of the most important fundamental processes in organic and bioorganic chemistry as peptides and proteins are formed by amide bonds. The N-tert-butyl amides are pharmaceutically important compounds in pharmaceutical industries 1 and 2 and serve as precursors to the ...