Preparation and properties of three analogues of [5-leucine] enkephalin, substrates for enzyme conversion studies

J Vičar, L Servítová, M Flegel, K Hauzer…

文献索引：Vicar; Servitova; Flegel; et al. Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 6 p. 1329 - 1334

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被引用次数: 3

摘要

Abstract Analogues of [5-Leu] enkephalin, prolonged by methionine on the N-terminus or, by lysine or methionine on the C-terminus were prepared by fragment condensation, purified by ion exchange chromatography or high-pressure liquid chromatography. The substances were characterised by their opioid activity in a test on guinea-pig ileum in comparison with the activity of [5-Leu] enkephalin.