Self??Promoted Nucleophilic Addition of Hexafluoro??2??propanol to Vinyl Ethers

…, B Crousse, D Bonnet??Delpon

文献索引：Di Salvo, Andrea; David, Marc; Crousse, Benoit; Bonnet-Delpon, Daniele Advanced Synthesis and Catalysis, 2006 , vol. 348, # 1-2 p. 118 - 124

全文：HTML全文

被引用次数: 10

摘要

Abstract In spite of its low nucleophilicity, hexafluoro-2-propanol easily adds to vinyl ethers, without catalyst, to afford a range of hexafluoroisopropyloxy acetals. This addition reaction also occurred in the presence of a competitive, more nucleophilic alcohol. Kinetic studies showed the importance of hydrogen bond parameters in the rate and course of the reaction.