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Synthetic Support for the α-Erythroidine Structure. The Conversion of α-to β-Erythrodine1

V Boekelheide, GC Morrison

文献索引:Boekelheide; Morrison Journal of the American Chemical Society, 1958 , vol. 80, p. 3905,3907

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被引用次数: 20

摘要

The synthesis of o-ethylphenyl tetrahydro-3-f~-any1 ketone (V) was undertaken first and, although the molecule is a relatively simple one, a number of obvious routes were tried without success before a satisfactory scheme was developed. The chief difficulty lay in obtaining &substituted tetrahydrofuranyl derivatives in a convenient fashion. Recently, Korte and Machleidt4 found that y-butyrolactone could be converted smoothly and in good yield ...