A Palladium??Catalyzed Regiospecific Synthesis of N??Aryl Benzimidazoles

…, KW Anderson, X Huang, HN Nguyen…

文献索引：Zheng, Nan; Anderson, Kevin W.; Huang, Xiaohua; Nguyen, Hanh Nho; Buchwald, Stephen L. Angewandte Chemie - International Edition, 2007 , vol. 46, # 39 p. 7509 - 7512

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被引用次数: 110

摘要

Benzimidazoles are a class of privileged core structures that are found in a broad spectrum of biologically active compounds such as nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonist,[1] lymphocyte specific kinase (Lck) inhibitor,[2] N-methyl-d- aspartate (NMDA) antagonist,[3] neuropeptide Y Y1 receptor antagonist,[4] nonpeptide thrombin inhibitor,[5] 5-lipoxygenase inhibitor,[6] factor Xa (FXa) inhibitor,[7] and poly ( ...