Regioselectivity of the amination of some nitroisoquinolines by liquid ammonia/potassium permanganate

…, A Barański, K Nowak, H Poradowska

文献索引：Wozniak, Marian; Baranski, Andrzej; Nowak, Krystyna; Poradowska, Henryka Liebigs Annalen der Chemie, 1990 , # 7 p. 653 - 657

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被引用次数: 10

摘要

Abstract 5-and 8-Nitroisoquinoline and some of their derivatives are aminated in a liquid ammonia solution of potassium permanganate to yield the corresponding 6-and 7-amino compounds. From 5, 7-dinitroisoquinoline the 6, 8-diamino derivative is obtained; 1- nitroisoquinoline has been found to be unreactive. FMO calculations made for a few nitroisoquinolines confirm the experimentally observed regioselectivity of the amination.