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Sulfur??Ylide??Mediated Synthesis of Functionalized and Trisubstituted Epoxides with High Enantioselectivity; Application to the Synthesis of CDP??840

…, HY Lee, J Richardson, DT Williams

文献索引:Aggarwal, Varinder K.; Bae, Imhyuck; Lee, Hee-Yoon; Richardson, Jeffery; Williams, David T. Angewandte Chemie - International Edition, 2003 , vol. 42, # 28 p. 3274 - 3278

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被引用次数: 94

摘要

The carbonyl group occupies a position of central importance in organic synthesis as it allows ready functionalization, for example, in the a, b, and g positions. Direct transformations into other versatile functional groups, such as alkenes and epoxides, further increase the importance of carbonyl groups in synthesis. The ability to conduct such transformations enantioselectively would be extremely useful, and toward this goal we ...