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Nucleophilic substitution reaction of 3-acetyl-1-methoxyindole and its application for the synthesis of novel 2-substituted methyl 2, 3-dihydro-1-methyl-3-oxo-5H-pyrido …

…, M Nakajou, T Teramoto, A Tanimoto…

文献索引:Somei, Masanori; Nakajou, Masahiro; Teramoto, Tsuyoshi; Tanimoto, Asuka; Yamada, Fumio Heterocycles, 1999 , vol. 51, # 8 p. 1949 - 1956

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被引用次数: 7

摘要

抄録: A simple synthetic route was established for 3-acetyl-1-methoxyindole, which was found to undergo nucleophilic substitution reactions selectively at the 2-position. Applying the reaction, novel 2-substituted methyl 2, 3-dihydro-1-methyl-3-oxo-5H-pyrido [4, 3-b] indole-4-carboxylates were prepared.