Journal of fluorine chemistry

Microwave fluorination: a novel, rapid approach to fluorination with Selectfluor®

GW Bluck, NB Carter, SC Smith, MD Turnbull

文献索引：Bluck, Gavin W.; Carter, Neil B.; Smith, Stephen C.; Turnbull, Michael D. Journal of Fluorine Chemistry, 2004 , vol. 125, # 12 p. 1873 - 1877

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被引用次数: 22

摘要

Fluorination of electron rich aromatic systems with electrophilic fluorination reagents such as Selectfluor® and Accufluor® is a well-established process. Herein we report results from investigations into the use of such procedures to perform rapid, small-scale fluorinations under microwave irradiation. We have investigated the transformation with a range of different substrates and discuss the effects of two key factors, namely reaction time and ...