Development of the Route of Manufacture of an Oral H1− H3 Antagonist

G Bret, SJ Harling, K Herbal, N Langlade…

文献索引：Organic Process Research and Development, , vol. 15, # 1 p. 112 - 122

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被引用次数: 9

摘要

... Organic Process Research & Development. ... Second, the process was quite lengthy, with several solvent and salt swaps. ... procedures to try and improve the selectivity for the desired product, and also try to streamline the hydrogenation and isolation procedure, ideally removing ...