Tetrahedron letters

Dinucleotide-analogous tetrapeptides. Specific triplex formation with complementary polynucleotides

T Yamazaki, K Komatsu, H Umemiya, Y Hashimoto…

文献索引：Yamazaki, Takahisa; Komatsu, Kazunori; Umemiya, Hiroki; Hashimoto, Yuichi; Shudo, Koichi; Kagechika, Hiroyuki Tetrahedron Letters, 1997 , vol. 38, # 48 p. 8363 - 8366

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被引用次数: 10

摘要

Several tetrapeptides (1–4) having two adenyl moieties at the side chains interacted complementary base-specifically with poly (dT) or poly (U). The hypochromic effects and CD spectra of the complexes suggested the formation of triplexes, which are more stable than those between natural ApA and the polynucleotides.