Synthesis and antiinflammatory activity of 5-phenacylidene-2-imino-4-oxazolidones

…, DD Nekrasov, AS Zaks, MI Korsheninnikova…

文献索引：Andreichikov, Yu. S.; Nekrasov, D. D.; Zaks, A. S.; Korsheninnikova, M. I.; Kolla, V. E.; Nikulina, S. N. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 2 p. 115 - 119 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 2 p. 157 - 160

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被引用次数: 3

摘要

We have synthesized and pharmacologically examined compounds of this series containing a phenacylidene substituent in position 5 of the oxazolidene ring. These compounds were synthesized by recycling 5-aryl-2, 3-dihydrofuran-2, 3-diones (I) upon reacting with cyanamides [i]. The reaction proceeds readily with a non-substituted cyanamide as well as with monoalkyl-and monoarylcyanamides with the formation of 5-phenacylidene-2-imino- ...