Journal of organometallic chemistry

A stereoselective process for the preparation of novel phosphonoalkylphosphinates

FH Ebetino, JD Berk

文献索引：Ebetino, Frank H.; Berk, Jeffrey D. Journal of Organometallic Chemistry, 1997 , vol. 529, # 1-2 p. 135 - 142

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被引用次数: 8

摘要

We have devised both a contiguous and a stepwise strategy for the synthesis of the pyridylaminomethane-based class of phosphonoalkylphosphinates (PAPs) that form via the intermediacy of the phosphonoethoxyaminomethane XIa. The PAPs result from condensation of picolines and phosphonoacetals in high chemoselective yield. Following reduction of aminopyridine IIIb, the unprecedented Pt (0)-catalyzed epimerization of the ...