Bulletin of the Chemical Society of Japan

Aromatic nucleophilic substitution of halobenzenes with amines under high pressure.

T Ibata, Y Isogami, J Toyoda

文献索引：Ibata, Toshikazu; Isogami, Yasushi; Toyoda, Jiro Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 1 p. 42 - 49

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被引用次数: 41

摘要

The nucleophilic substitution reactions of aromatic halides having electron-attracting groups on ortho or para position with various primary and secondary amines were accelerated by high pressure to give the corresponding N-substituted anilines in high yields. The bulkiness of amines affects its reactivity to lower the yields of the products. Although the secondary amines are usually less reactive than primary amines, cyclic secondary amines such as ...