Development of a kilogram-scale synthesis of cis-LC15-0133 tartrate, a potent dipeptidyl peptidase IV inhibitor

BC Kim, KY Kim, HB Lee, H Shin

文献索引：Organic Process Research and Development, , vol. 12, # 4 p. 626 - 631

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被引用次数: 12

摘要

... Organic Process Research & Development. ... provide clear description of the chemical identity of the final API, we were required to develop a process to prepare ... The combined organic layer was concentrated under reduced pressure to give the crude brown oil 4 (3.29 kg), which ...