An efficient approach to chiral C8/C9-piperazino-substituted 1, 4-benzodiazepin-2-ones as peptidomimetic scaffolds

S Butini, E Gabellieri, PB Huleatt…

文献索引：Journal of Organic Chemistry, , vol. 73, # 21 p. 8458 - 8468

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被引用次数: 18

摘要

... The organic phase was separated and dried then the solvent was removed in vacuo. The residue was purified by column chromatography (n-hexane/ EtOAc 1:1; Rf 0.33) to afford the title compound as yellow prisms (36) Roy, AD; Subramanian, A.; Roy, R. J. Org. Chem. ...