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The Journal of Organic Chemistry

Resolution of trifluoromethylcarbinols

DM Feigl, HS Mosher

文献索引:Feigl,D.M.; Mosher,H.S. Journal of Organic Chemistry, 1968 , vol. 33, # 11 p. 4242 - 4245

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被引用次数: 18

摘要

When an enantiomerically pure reagentlo (R 111) is allowed to react with a carbinol (I) consisting of a mixture of enantiomers, a mixture of epimers (R, R IV and X, R IV) will result. If there is no racemization of carbinol (I), reagent (111), or products (IV), and if there is no kinetic resolution during this process, then the mixture of epimers (R, R IV and S, R IV) will be formed in exactly the same ratio as the enantiomers initially present. Therefore, any ...