Tetrahedron letters

α-Iodocycloalkenones: Synthesis of (±)-epibatidine

NS Sirisoma, CR Johnson

文献索引：Sirisoma, Nilantha S.; Johnson, Carl R. Tetrahedron Letters, 1998 , vol. 39, # 15 p. 2059 - 2062

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被引用次数: 45

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A synthesis of the non-opiate analgesic alkaloid epibatidine was achieved in 13 steps and 13% overall yield starting from 1,3-cyclohexadiene using in a key step a modified Stille coupling reaction on an α-iodocyclohexenone. ... The synthesis of epibatidine from ...