Synthesis

Novel synthetic strategy of N-arylated heterocycles via sequential palladium-catalyzed intra-and inter-arylamination reactions

R Omar-Amrani, R Schneider, Y Fort

文献索引：Omar-Amrani, Rafik; Schneider, Raphael; Fort, Yves Synthesis, 2004 , # 15 p. 2527 - 2534

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被引用次数: 21

摘要

Abstract The use of an in situ generated Pd (0) catalyst associated to N, N′-bis (2, 6- diisopropylphenyl) dihydroimidazol-2-ylidene (SIPr) as a ligand and t-BuONa as the base for sequential intra-followed by intermolecular aryl amination is described. The method has been applied to the synthesis of N-arylated five-, six-and seven-membered nitrogen heterocycles.