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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Synthesis of potential metabolites of dibenz [a, j] acridine: dihydro diols and phenols

CA Rosario, GM Holder, CC Duke

文献索引：Rosario, Christopher A.; Holder, Gerald M.; Duke, Colin C. Journal of Organic Chemistry, 1987 , vol. 52, # 6 p. 1064 - 1072

全文：HTML全文

被引用次数: 16

摘要

Dibenz [aj] acridine (1) is a polycyclic azaaromatic hydrocarbon found in tobacco smoke condensate'and urban atmosphere2 and possesses carcinogenic proper tie^.^ It is expected, by analogy with other polycyclic hydrocarbon~,~ that the biological activation of 1 proceeds through dihydro diols and diol epoxides, and metabolism in vitro with liver microsomes from 3-methylcholanthrene pretreated animals has demonstrated the ...

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

~%

二苯并(A,J)丫啶结构式

二苯并(A,J)丫啶

3,4-DIHYDRODIBENZ(A,J)ACRIDINE结构式

3,4-DIHYDRODIBE...

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

详细

1,4,8,9-tetrahydrodibenzo[a,j]acridine结构式

1,4,8,9-tetrahy...

~%

二苯并(A,J)丫啶结构式

二苯并(A,J)丫啶

3,4-DIHYDRODIBENZ(A,J)ACRIDINE结构式

3,4-DIHYDRODIBE...

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

详细

未登录结构式

~78%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

1-(二甲基胺甲基)萘酚结构式

1-(二甲基胺甲基)萘酚

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

5,6,7,8-四氢-2-萘胺结构式

5,6,7,8-四氢-2-萘胺

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

1,2,3,4-TETRAHYDRODIBENZ(A,J)ACRIDINE结构式

1,2,3,4-TETRAHY...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

二苯并(A,J)丫啶结构式

二苯并(A,J)丫啶

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

1,4,8,9-tetrahydrodibenzo[a,j]acridine结构式

1,4,8,9-tetrahy...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

trans-3,4-dihydroxy-1,2,3,4-tetrahydrodibenz(a,j)acridine结构式

trans-3,4-dihyd...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

trans-3,4-diacetoxy-1,2,3,4,8,9-hexahydrodibenz[a,j]acridine结构式

trans-3,4-diace...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

trans-3,4-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenz(a,j)acridine结构式

trans-3,4-bis(b...

~%

Dibenz(a,j)acridine-3,4-diol, 3,4-dihydro-, trans-结构式

Dibenz(a,j)acri...

1-(二甲基胺甲基)萘酚结构式

1-(二甲基胺甲基)萘酚

~%

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

5,6,7,8-四氢-2-萘胺结构式

5,6,7,8-四氢-2-萘胺

~%

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

1,2,3,4-TETRAHYDRODIBENZ(A,J)ACRIDINE结构式

1,2,3,4-TETRAHY...

~%

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

1,4,8,9-tetrahydrodibenzo[a,j]acridine结构式

1,4,8,9-tetrahy...

~%

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

二苯并(A,J)丫啶结构式

二苯并(A,J)丫啶

~%

1,4-dihydrodibenz[a,j]acridine结构式

1,4-dihydrodibe...

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

5,6,8,9-tetrahydrodibenz[a,j]acridine结构式

5,6,8,9-tetrahy...

详细

1-(二甲基胺甲基)萘酚结构式

1-(二甲基胺甲基)萘酚

~%

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

5,6,7,8-四氢-2-萘胺结构式

5,6,7,8-四氢-2-萘胺

~%

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

1,2,3,4-TETRAHYDRODIBENZ(A,J)ACRIDINE结构式

1,2,3,4-TETRAHY...

~%

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

二苯并(A,J)丫啶结构式

二苯并(A,J)丫啶

~%

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

~%

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

1,4,8,9-tetrahydrodibenzo[a,j]acridine结构式

1,4,8,9-tetrahy...

~%

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

1,4,10,13-tetrahydrodibenzo[a,j]acridine结构式

1,4,10,13-tetra...

~%

二苯并(A,J)丫啶结构式

二苯并(A,J)丫啶

3,4-DIHYDRODIBENZ(A,J)ACRIDINE结构式

3,4-DIHYDRODIBE...

1,2-Dihydrodibenz(a,j)acridine结构式

1,2-Dihydrodibe...

Synthesis of potential metabolites of dibenz [a, j] acridine...

[Journal of Organic Chemistry, , vol. 52, # 6 p. 1064 - 1072]