A series of 5, 6-disubstituted 1, 2, 3-trisilaindanes (2− 5) were synthesized via a colbalt- catalyzed [2+ 2+ 2] cycloadition of dialkyne 7 with a monoalkyne (8− 11) and were structurally characterized (including crystal structure analyses in the case of 3− 5). The 1, 2, 3-trisilaindane backbone of 2− 5 proved to be very reactive toward oxidation agents. Compounds 2 and 3 are nominally silicon analogues of the musk odorant phantolide; ...
