AN IMPROVED SYNTHESIS OF 4-HYDROXY AND 4′-METHOXYBIPHENYL-2-CARBOXYLIC ACIDS

G Estenne, P Dodey, P Renaut…

文献索引：Estenne, Genevieve; Dodey, Pierre; Renaut, Patrice; Leclerc, Gerard Organic Preparations and Procedures International, 1995 , vol. 27, # 4 p. 500 - 503

全文：HTML全文

被引用次数: 0

摘要

Biphenyl derivatives of type 1 were needed as part of our research on non peptidic A11 antagonists.'Previously these compounds had been synthesized by radical coupling2 of diazonium salts or by the Ullmann reaction.'" Compound la had been obtained previously in low yield (10%) by the Gomberg-Bachman reaction between o-anisidine and methyl ben~ oate;~ this route, however, led to a mixture of products. Over the past ten years, new ...