Although water is the most abundant chemical on our planet, its use has been neglected as a medium or a solvent in organic chemistry for many decades. This ignorance has been the result of the belief that water destroys many organic reagents and chemicals and is only safe to be used in workup procedures. This opinion was widespread until Grieco [11. Grieco PA, Garner P, He Zm. “Micellar” catalysis in the aqueous intermolecular Diels-Alder reaction: rate ...
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