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Synthesis of benzimidazoles by copper-catalyzed aerobic oxidative domino reaction of 1, 2-diaminoarenes and arylmethyl halides

D Qiu, H Wei, L Zhou, Q Zeng

文献索引:Qiu, Dezhi; Wei, Haidong; Zhou, Lihong; Zeng, Qingle Applied Organometallic Chemistry, 2014 , vol. 28, # 2 p. 109 - 112

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被引用次数: 5

摘要

Benzimidazoles, an important class of nitrogen-containing heterocycles, widely occur in natural products,[1–4] and have extensively demonstrated important bioactivities and medical value.[5] Thus substantial efforts have been made in searching for new synthetic strategies to assemble this structure. They are commonly synthesized via reactions of benzoic acids, acid anhydrides, esters and acid chlorides.[6–8] Benzimidazoles can also ...