Abstract: For the purpose of the development of immunoassays for wide-scale screening, isoflavones suitable for attachment to a hapten were prepared. A new cyclisation reaction allowed the direct conversion of 2-(acyloxy) deoxybenzoins to 2-alkylisoflavones by treatment with chlorotrimethylsilane and triethylamine in dimethylformamide. Key words: immunoassay, genistein, cyclisation, 2-(acyloxy) deoxybenzoins, 2-alkylisoflavones
[Devi, Nirada; Jain, Niveta; Krishnamurty, H. G. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 8 p. 874 - 875]