Tetrahedron letters

Copper-catalyzed conjugate addition of organomagnesium reagents to α, β-ethylenic esters: A simple high yield procedure.

G Cahiez, M Alami

文献索引：Cahiez, Gerard; Alami, Mouad Tetrahedron Letters, 1990 , vol. 31, # 51 p. 7425 - 7428

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被引用次数: 20

摘要

Abstract The conjugate addition of organomagnesium reagents to α, β-ethylenic esters is performed in THF, at room temperature (30 min to 1.5 h), in the presence of CuCl (3%) and Me 3 SiCl (1.2 eq.). Good yields of 1, 4-addition products are obtained according to this very simple procedure.