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Tetrahedron Letters

Removal of n-benzyl-and n-benzyloxymethyl substituents from substituted uracils with boron tribromide

NG Kundu, RP Hertzberg, SJ Hannon

文献索引:Kundu, Nitya G.; Hertzberg, Robert P.; Hannon, Stephen J. Tetrahedron Letters, 1980 , vol. 21, p. 1109 - 1112

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被引用次数: 21

摘要

Abstract N 1, N 3-Dibenzyl uracil derivatives have been successfully deblocked by using boron tribromide in refluxing xylene. Also N 1, N 3-dibenzyloxy methyl uracil derivatives can be easily converted to uracils by treatment with boron tribromide in benzene in the cold and subsequent boiling of the intermediate with water.