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Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human …

PM Vyas, S Roychowdhury, PM Woster…

文献索引:Biochemical Pharmacology, , vol. 70, # 2 p. 275 - 286

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被引用次数: 42

摘要

... Biochemical Pharmacology. Volume 70, Issue 2, 15 July 2005, Pages 275–286. ... 2). Thus, to probe the proposed hypothesis, in addition to SMX-NOH and DDS-NOH, we synthesized three hydroxylamine metabolites/analogues of DDS: DDS-dihydroxylamine (DDS-diNOH), 4 ...