Tetrahedron Letters

A new synthesis of the benzo [c] phenanthridines nornitidine, noravicine, and isodecarine, based on a microwave-assisted electrocyclic reaction of the aza 6π-electron …

K Kohno, S Azuma, T Choshi, J Nobuhiro, S Hibino

文献索引：Kohno, Kakujiro; Azuma, Shuhei; Choshi, Tominari; Nobuhiro, Junko; Hibino, Satoshi Tetrahedron Letters, 2009 ,  vol. 50,  # 5  p. 590 - 592

全文：HTML全文

被引用次数: 26

摘要

A new and versatile synthetic route to a benzophenanthridine alkaloid was developed by a bond formation between C4b and N5 on the benzo [c] phenanthridine nucleus, using a microwave-assisted electrocyclic reaction of the aza 6π-electron system. This strategy was successfully used to synthesize nornitidine (1b), noravicine (1d), and isodecaline (1f).