Allenyltrialkylstannanes were found to react with various allylic acetates in the presence of catalytic amounts of Pd (PPhd4 under mild neutral conditions, providing a novel approach for obtaining the 1, 5-enyne carbon skeleton. The regioselectivity of propargylation depends largely on the electron-withdrawing properties of the substituents at the two ends of the allylic system: substitution occurs at the end of closer proximity to the more electronegative ...
