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Steroids

Reduction of 3α-hydroxy-5β-CHOL-6-EN-24-OIC acid to lithocholic acid in rats

K Kimura, O Michio

文献索引:Kimura, Koji; Ogura, Michio Steroids, 1988 ,  vol. 51,  # 3-4  p. 337 - 348

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摘要

Abstract After [24-14 C] Δ 6-lithocholic acid was injected into the cecum of rats,[14 C] lithocholic acid was identified as a metabolite in feces. When the labeled Δ 6-bile acid was injected intraperitoneally into bile-fistula rats, radioactivity excreted in bile was contained most abundantly in the taurine-conjugated fraction of bile acids. In the fraction, taurine conjugate of [14 C] Δ 6-lithocholic acid but of neither [14 C] lithocholic acid nor other bile ...