Lipase-catalyzed irreversible transesterifications using enol esters as acylating reagents: preparative enantio-and regioselective syntheses of alcohols, glycerol …

YF Wang, JJ Lalonde, M Momongan…

文献索引：Wang,Y.F.; Lalonde,J.J.; Momongan,M. Journal of the American Chemical Society, 1988 , vol. 110, p. 7200

全文：HTML全文

被引用次数: 534

摘要

Abstract: Isopropenyl and vinyl esters have been found to be useful for lipase-catalyzed stereoselective acylation of a number of hydroxy compounds including glycerol and serinol derivatives, ferrocenylethanol, sugars, and other alcohols. The reactions are faster, more selective, and easier to optimize than other transesterifications using alkyl esters as acylating reagents. The alcohol freed from the transesterification rapidly tautomerizes to ...