Continuing our broad study of the microbiological oxygenation of simple monocyclic systems, a series of N-cycloalkylamides and N, N-dicycloalkylamides waa subjected to fermentation by Sporotrichum sulfurescm. Consonant with the hypothetical enzyme- substrate model proposed earlier, N-cyclododecylacetamide was monooxygenated at the 5, 6, and 7 positions, while a variety of N-cyclohexyhmides and N-cycloheptylamides ...
