Identification of Ligand-Binding Regions of P-Glycoprotein by Activated-Pharmacophore Photoaffinity Labeling and Matrix-Assisted Laser Desorption/Ionization–Time- …
... represents one possible experimental strategy to characterize those regions of the protein molecule in which an interaction with low-molecular-mass ligands takes ... that R influences pharmacological activity solely by its contribution to overall lipophilicity of the molecules. ...
