Biaryl motifs are widely present in a variety of natural products and drugs, 1 such as Diovan® and Micardis® as hypertension medicine (Fig. 1). Their sales are up to billion and possess large values. 2 and 3 A cheap and efficient way to prepare such fine chemicals with biaryl motif is of great interest. ... Structures of Diovan® and Micardis®. Structures of Diovan® and Micardis®. ... The aryl–aryl bond formation was first reported by Ullmann in 1901 using ...