Electrochemical construction of the diaryl ethers: a synthetic approach to o-methylthalibrine

…, T Tanabe, Y Kawabata, Y Ishikawa, S Nishiyama

文献索引：Naito, Yu; Tanabe, Takamasa; Kawabata, Yuki; Ishikawa, Yuichi; Nishiyama, Shigeru Tetrahedron Letters, 2010 , vol. 51, # 36 p. 4776 - 4778

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被引用次数: 7

摘要

Electrochemical dimerization of halogenated p-hydroxyphenylacetic acid derivatives followed by Zn reduction provided the corresponding diaryl ethers. Manipulation of the reduction step using several procedures increased its efficiency, which enabled the construction of o-methylthalibrine, an isoquinoline-class alkaloid.