Tetrahedron

Cobalt-catalyzed aerobic oxidative cyclization of β, γ-unsaturated oximes

W Li, P Jia, B Han, D Li, W Yu

文献索引：Li, Weifei; Jia, Pingjing; Han, Bing; Li, Dianjun; Yu, Wei Tetrahedron, 2013 , vol. 69, # 15 p. 3274 - 3280

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被引用次数: 11

摘要

Cobalt complex Co (nmp) 2 can efficiently catalyze the aerobic oxidative 5-exo cyclization of β, γ-unsaturated oximes to afford isoxazolines. The key cyclization step involves the generation of carbon-centred radicals. The products are largely dependent on the reaction conditions. The oxidative termination products 2 were produced predominantly when the reaction was carried out in i-PrOH, whereas the reductive termination products 3 were ...