Synthesis and activity of combretastatin A-4 analogues: 1, 2, 3-thiadiazoles as potent antitumor agents

M Wu, Q Sun, C Yang, D Chen, J Ding, Y Chen…

文献索引：Wu, Maojiang; Sun, Qiming; Yang, Chunhao; Chen, Dongdong; Ding, Jian; Chen, Yi; Lin, Liping; Xie, Yuyuan Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 4 p. 869 - 873

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被引用次数: 77

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of 4,5-disubstitute-1,2,3-thiadiazole compounds were designed and synthesized as potent anticancer agents, some of them exhibited excellent in vitro and in vivo inhibitory activity. ... Malignant tumor is one of the most serious threats against human health in the world, and the clinical ...