Tetrahedron

The alkylation of menthyl hippurate and some related materials: a reinvestigation.

…, R Thangarasa, NK Foley, DJ Ager, DE Froen, RC Klix

文献索引：McIntosh, John M.; Thangarasa, Rasiah; Foley, Nancy K.; Ager, David J.; Froen, Diane E.; Klix, Russell C. Tetrahedron, 1994 , vol. 50, # 7 p. 1967 - 1974

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被引用次数: 14

摘要

Benzylation of chiral esters of N-acylglycines using various bases and additives was examined. No C-alkylation was observed with one equivalent of base. Diastereoselectivities were dependent on the amount of additive, the nature of the N-acyl group, and the chiral ester. A model to account for the degree and sense of the stereoselectivity is proposed.