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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Heck–Matsuda Arylation as a Strategy to Access Kavalactones Isolated from Polygala sabulosa, Piper methysticum, and Analogues

C Soldi, AV Moro, MG Pizzolatti…

文献索引：Soldi, Cristian; Moro, Angelica V.; Pizzolatti, Moacir G.; Correia, Carlos R. D. European Journal of Organic Chemistry, 2012 , # 19 p. 3607 - 3616

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被引用次数: 9

摘要

Abstract Herein, we describe the total syntheses of three bioactive pyrones isolated from Polygala sabulosa (ie, 1, 4, and 7) and eight isolated from Piper methysticum (ie, 8–10, 13, 15, and 18–20) using the Heck–Matsuda arylation as the key strategy. The evaluation of this methodology by employing different arenediazonium tetrafluoroborates revealed that the Heck arylation was more efficient when the olefin undergoing arylation possessed the ...

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