Organic letters

Organocatalyzed Asymmetric Synthesis of Dihydrodibenzofurans Based on a Dienamine Process

ZY Wang, WT Wong, D Yang

文献索引：Wang, Zi-Yu; Wong, Wing-Tak; Yang, Dan Organic Letters, 2013 , vol. 15, # 19 p. 4980 - 4983

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被引用次数: 11

摘要

The first organocatalyzed asymmetric method for the synthesis of dihydrodibenzofurans based on a dienamine process has been developed. This two-step protocol works with a broad range of substrates and delivers only the cis-diastereomer in good yield with up to 91% ee. The enantioenriched products have been transformed to highly functionalized and partially hydrogenated dibenzofurans in excellent diastereoselectivities.