Construction of Substituted Benzene Rings by Palladium??Catalyzed Direct Cross??Coupling of Olefins: A Rapid Synthetic Route to 1, 4??Naphthoquinone and Its …

P Hu, S Huang, J Xu, ZJ Shi…

文献索引：Hu, Peng; Huang, Shijun; Xu, Jing; Shi, Zhang-Jie; Su, Weiping Angewandte Chemie - International Edition, 2011 , vol. 50, # 42 p. 9926 - 9930

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被引用次数: 19

摘要

Benzene rings can be found in about 30% of all industrial chemicals and in over half of the top 50 drugs.[1] This fact clearly illustrates the immense scientific and commercial value of aromatic compounds in modern society. These compounds usually bear more than one substituent on the benzene ring, and are traditionally constructed by the stepwise introduction of substituents through electrophilic aromatic substitution (Scheme 1a). ...