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The Journal of Organic Chemistry

Di-, tri-, tetra-, and pentacationic alkylammonium salts. Ligands designed to prevent the nonspecific electrostatic precipitation of polyanionic, functionalized …

JFW Keana, Y Wu, G Wu

文献索引:Keana, John F. W.; Wu, Yexin; Wu, Guanli Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2571 - 2576

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被引用次数: 23

摘要

This work relates to the use of organic functionalized heteropolytungstates (HPTs) as protein- specific electron microscopy labels. The objective is the development of a polycationic ligand that prevents the nonspecific precipitation reaction observed between certain polycationic biomolecules and polyanionic heteropolytungstates. Simple tetra-and pentaammonium salts between Keggin HPT lb or Dawson HFT 2b and amines 3-6 or ...