Controlling the biological effects of spermine using a synthetic receptor
…, J Leclaire, R Pérez-Fernández, S Otto
文献索引：Vial, Laurent; Ludlow, R. Frederick; Leclaire, Julien; Perez-Fernandez, Ruth; Otto, Sijbren Journal of the American Chemical Society, 2006 , vol. 128, # 31 p. 10253 - 10257
Polyamines play an important role in biology, yet their exact function in many processes is poorly understood. Artificial host molecules capable of sequestering polyamines could be useful tools for studying their cellular function. However, designing synthetic receptors with affinities sufficient to compete with biological polyamine receptors remains a huge challenge. Binding affinities of synthetic hosts are typically separated by a gap of several ...
