Tetrahedron

Hydroxylation of ionized aromatics including carboxylic acid or amine using recombinant Streptomyces lividans cells expressing modified biphenyl dioxygenase …

…, S Horinouchi, H Takahashi, K Iguchi, S Harayama…

文献索引：Shindo, Kazutoshi; Nakamura, Ryoko; Chinda, Ikuko; Ohnishi, Yasuo; Horinouchi, Sueharu; Takahashi, Haruko; Iguchi, Kazuo; Harayama, Shigeaki; Furukawa, Kensuke; Misawa, Norihiko Tetrahedron, 2003 , vol. 59, # 11 p. 1895 - 1900

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被引用次数: 11

摘要

The bphA1 (2072) A2A3A4 gene cluster codes for a shuffled biphenyl dioxygenase holoenzyme with broad substrate specificity. These bphA1 (2072) A2A3A4 genes were expressed in the actinomycetes Streptomyces lividans using a thiostrepton-inducible promoter PtipA. Biotransformation experiments of various aromatics including carboxylic acid or amine in their molecular structure, such as 1-naphthoic acid, 2-(1-naphthyl) acetic ...