Pharmacological activity of analogs and cycloanalogs of pyracetam

…, TA Gudasheva, SS Trofimov, RU Ostrovskaya…

文献索引：Popova, R. Ya.; Gudasheva, T. A.; Trofimov, S. S.; Ostrovskaya, R. U.; Skoldinov, A. P. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 12 p. 858 - 864 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 12 p. 1439 - 1445

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摘要

58, 4 8, 1 7, 6 60 3 8, 5 7, 0'61, 9 8, 9 6, 6 i60, 3 8, 5 7, 0 61, 9 8, 9 6, 6 aon grade II alumina, benzene-ethyl acetate-methanol, 4: 4: 1. bLiterature bp [4] 126~(2 mm). CLiterature bp [4] 125-126~(i mm). the reaction with ethyl B-bromopropionate (n= 2) required heating on the water bath. The alkoxycarbonyl derivatives (IIIa-g)(Table 2) were isolated by vacuum distillation, or by chromatography on A1203. Aminolysis of the esters (IIIa-g) was effected ...