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Tetrahedron letters

Facile conversion of carboxamides to nitriles

K Mai, G Patil

文献索引:Mai, Khuong; Patil, Ghanshyam Tetrahedron Letters, 1986 , vol. 27, # 20 p. 2203 - 2206

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被引用次数: 34

摘要

Abstract Alkyl, aralkyl, aryl, heteroaryl carboxamides bearing various functionalities are readily converted to the corresponding nitriles in good yields using the liquid “diphosgene”, trichloromethyl chloroformate, as dehydrating agent. In many cases, the procedure does not